Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years. Researchers ...

Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

Researchers from École Polytechnique Fédérale de Lausanne, Switzerland (EPFL) have mapped the molecular workings of potassium ion channels within the brain. The study titled, “A kinetic map of the ...

The neurological disease epilepsy afflicts about 50 million people worldwide and is difficult to treat. Current treatments leave around 30% of patients with inadequate control of their seizures, ...

Scientists have uncovered the atomic structure of KR2, a light-driven transporter for sodium ions which had only recently been discovered. Based on the structural information the team then identified ...

A RIKEN study shows that squeezing the right amount of potassium ions between the atomic layers of molybdenum disulfide can turn it from a semiconductor into a metal, superconductor or insulator. The ...

Metrion Biosciences Ltd (“Metrion”), the specialist ion channel contract research and drug discovery company, announced that it has acquired a portfolio of more than 2,000 small molecule potassium ...